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Metronidazole has proven evidence of mutagenic exercise in various in vitro bacterial assay devices. Also, a dose-relevant increase in the frequency of micronuclei was noticed in mice soon after intraperitoneal injections. An increase in chromosomal aberrations in peripheral blood lymphocytes was reported in people with Crohn’s condition who have been taken care of with 200 to 1200 mg/day of metronidazole for 1 to 24 months.

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